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KMID : 0604520070330040275
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Journal of the Society of Cosmetic Scientists of Korea
2007 Volume.33 No. 4 p.275 ~ p.280
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Application as a Cosmeceutical Ingredient of Extract from Euphorbia jolkini
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Lee Dae-Woo
Kim Young-Jin
Kim Young-Sil
Eom Sang-Yong
Kim Jong-Heon
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Abstract
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In this study, we evaluate anti-oxidation, whitening and anti-inflammatory efficacies of Euphorbia jolkini extract for application as a cosmeceutical ingredient. We separated 5 fractions from Euphorbia jolkini extract (70 % MeOH) by MPLC. First and 5th fractions showed a supressive effect on Mn-SOD synthesis in the normal human fibroblasts. They inhibited melanogensis in the B16-F10 melanma cells. Furthermore, 1st and 5th fractions reduced the amounts of , IL-6, COX-II and total NO secreted from the normal human fibroblasts. These results suggest that Euphorbia jolkini extract may be used as an active ingredient in cosmetics.
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KEYWORD
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Euphorbia jolkini, whitening, anti-inflammation, IL-6
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